MELBOURNE: These days, we don’t think much about being able to access a course of antibiotics to head off an infection. But that wasn’t always the case – antibiotics have been available for less than a century. Before that, patients would die of relatively trivial infections that became more serious.
Some serious infections, such as those involving the heart valves, were inevitably fatal. Other serious infections, such as tuberculosis, weren’t always fatal. Up to a half of people died within a year with the most severe forms, but some people recovered without treatment and the remainder had ongoing chronic infection that slowly ate away at the body over many years.
Once we had antibiotics, the outcomes for these infections were much better.
You’ve probably heard of Alexander Fleming’s accidental discovery of penicillin, when fungal spores landed on a plate with bacteria left over a long weekend in 1928.
But the first patient to receive penicillin was an instructive example of the impact of treatment. In 1941, Constable Albert Alexander had a scratch on his face that had become infected.
He was hospitalised but despite various treatments, the infection progressed to involve his head. This required removing one of his eyes.